The Centre for Proteomic Research combines in-depth expertise with internationally competitive facilities for the large-scale characterisation of proteins expressed in health and disease. Proteins are the ultimate effectors of essentially all cellular processes and constitute the vast majority of therapeutic drug targets. Thus, the systematic analysis of proteins and in particular their patterns of expression, interactions and modifications - proteomics - is now a valuable approach for defining key cellular processes in molecular detail. In addition to in-house research, the Centre provides resources for other investigators, undertakes collaborations and provides a contract service for academics and commercial users.
iTRAQ
An alternative
non-gel based approach is the use of iTRAQ for the
quantitative study of gene expression at the proteome
level....(more)
AQUA
A powerful approach for the absolute quantification of proteins and phosphoproteins without recourse to antibodies...(more)
GeLC - MS/MS
GeLC- MS/MS is a powerful yet simple approach for shotgun proteomic analyses. Samples are separated using 1-D SDS ...(more)
MudPIT
MudPIT (multidimensional protein identification technology) is a non-gel approach for the identification of diverse proteins from complex mixtures. ...(more)
